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Found 3 Enz. Inhib. hit(s) with BLAST sequence identity > 85%
TargetNucleoprotein TPR(Mus musculus)
Chinese Academy Of Sciences (Cas)

Curated by ChEMBL
LigandPNGBDBM50165465(CHEMBL3797579)
Affinity DataIC50:  1.30nMAssay Description:Inhibition of TPR-MET in mouse BAF3 cells assessed as reduction in cell proliferation after 72 hrs by SRB or MTT assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor/Nucleoprotein TPR(Mus musculus)
Chinese Academy Of Sciences (Cas)

Curated by ChEMBL
LigandPNGBDBM163243(US9062045, Comparator No. 1 (JNJ-38877605))
Affinity DataIC50:  8.60nMAssay Description:Inhibition of TPR-MET in mouse BAF3 cells assessed as reduction in cell proliferation after 72 hrs by SRB or MTT assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNucleoprotein TPR(Mus musculus)
Chinese Academy Of Sciences (Cas)

Curated by ChEMBL
LigandPNGBDBM50165469(CHEMBL3797911)
Affinity DataIC50:  80nMAssay Description:Inhibition of TPR-MET in mouse NIH/3T3 cells assessed as inhibition of cell proliferation after 72 hrs by SRB or MTT assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed